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Professor John Standford, a bacteriologist, explains why exposure to germs
is so important
The
idea that germs are bad for us
came out of the early part of the last century when there was a lot of
concentration on teaching people about bacteria and the germ theory of
infection.
The scientists that
became most certain that all germs are bad for us, according to Prof Standford,
were the pharmacologists who were developing drugs specifically to kill
germs and this
was built on by people selling disinfectants and other household products.
But Prof Standford
says that in fact the really important ones that you need to kill are
a very small number amongst the great majority:
"When
you start as a bacteriologist you learn about the organisms that cause
disease. As you progress further in your knowledge of this, you realise
that there are many close relatives of the organisms that cause disease
which are in your surroundings and it’s by meeting these that you develop
protection. The hygiene hypothesis is part of a story of increasing separation
from our environment and also that the environment has itself changed.
And the two things together have resulted in our immune system not getting
the essential learning processes that it really needs".
He continues:
"Just as when
you are a small child and you learn languages and your brain is important
in the way in which you learn languages, then silently and behind the
scenes, the immune system is also learning. But it learns from the things
that you inadvertently need. The things you eat, the things you swallow,
the things that gets into cuts, the things that get into your eye, almost
any place where you have direct contact with the environment, the immune
system learns from it."
Prof
Standford believes that it is not just that we separate ourselves from
the environment by washing off the environment or by being careful not
to touch dirty things, it is basically the way in which we no longer contact
the general outside environment at all. Children
today watch television a lot of the time and play with computers a lot
of the time. There are many pressures which prevent children from being
able to go out and play outside as they used to be able to do.
Prof Standford's research
over the last twenty years, was started off aimed at treating tuboculosis,
preventing TB, improving the treatment of lebrosy, preventing the children
of leprosy patients developing the disease as they grew older. However,
he says that the way in which it has progressed as been quite surprising:
"As
we were beginning to understand the immune changes that we were capable
of inducing, the scale and the scheme for this was very much greater.
Today we’re very much interested in the prevention and potential treatment
of cancers and in the prevention of allergic diseases. My current dream
is that we can develop a vaccine which will replace the effects of too
much hygiene and keeping ourselves too far away from the environment.
Yes, there are germs that are bad for you but the great majority of them
are not bad for you at all, others that are neutral and others are definitely
there and benefit you. This may seem like heretical to many people but
if you work in this field it is not heretical at all, it’s what we’ve
all come to learn to believe."
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